Table 2.
Laboratory data analysed in the study.
| Feature | Unit | Missing | No bacteraemia | Bacteraemia | p–value | ROCs (95%CI) |
|---|---|---|---|---|---|---|
| PCT | ng/ml | 1.5% | 0.3 (0.1–1.0) | 1.6 (0.4–5.4) | <0.001* | 0.729 (0.679–0.779) |
| CRP | mg/dl | 0.4% | 12.9 (7.9–20.4) | 15.0 (9.6–22.8) | 0.020 | 0.569 (0.512–0.626) |
| LBP | µg/ml | 1.1% | 23.1 (15.6–35.4) | 29.7 (19.7–44.25) | <0.001* | 0.610 (0.553–0.667) |
| IL-6 | pg/ml | 1.7% | 42.8 (19.2–99.9) | 49.6 (28.9–130.0) | 0.028 | 0.566 (0.508–0.623) |
| Fib | mg/dl | 6.0% | 607 (446–752) | 613 (490–714) | 0.875 | 0.505 (0.447–0.563) |
| SI | µg/dl | 1.7% | 26.0 (14.8–57.0) | 21.0 (12.3–46.8) | 0.042 | 0.561 (0.502–0.619) |
| TP | g/l | 2.4% | 61.6 (55.8–67.5) | 60.5 (53.2–65.8) | 0.062 | 0.556 (0.498–0.614) |
| ALAT | U/L | 1.9% | 25.0 (15.0–45.0) | 33.0 (18.0–64.0) | 0.005 | 0.585 (0.526–0.643) |
| Alb | g/l | 2.4% | 31.3 (27.9–35.1) | 29.5 (25.6–33.1) | <0.001* | 0.603 (0.546–0.673) |
| Bili | mg/dl | 3.9% | 0.6 (0.5–1.0) | 0.8 (0.6–1.4) | <0.001* | 0.616 (0.558–0.673) |
| γ–GT | U/L | 2.4% | 63 (30–130) | 102 (44–260) | <0.001* | 0.617(0.559–0.675) |
| Crea | mg/dl | 0.4% | 0.9 (0.8–1.3) | 0.9 (0.8–1.3) | 0.707 | 0.511 (0.452–0.570) |
| LDH | U/L | 4.3% | 220 (168–312) | 200 (157–286) | 0.161 | 0.543 (0.485–0.602) |
| Hb | g/dl | 2.4% | 10.0 (9.0–11.7) | 10.0 (9.1–10.9) | 0.340 | 0.529 (0.473–0.584) |
| Plt | G/l | 2.4% | 208 (116–326) | 190 (134–279) | 0.426 | 0.524 (0.457–0.580) |
| WBC | G/l | 2.4% | 8.7 (5.4–13.6) | 8.7 (5.5–12.6) | 0.629 | 0.486 (0.428–0.543) |
| NeuR | % | 7.1% | 75.5 (63.9–82.8) | 79.5 (67.2–86.6) | 0.021 | 0.570 (0.510–0.631) |
| EosR | % | 4.3% | 0.9 (0.2–2.5) | 0.8 (0.2–1.9) | 0.308 | 0.531 (0.472–0.589) |
| IL-10** | pg/ml | 0.0% | 2.2 (1.4–4.6) | 3.2 (1.7–7.3) | 0.002 | 0.589 (0.532–0.645) |
| IL-17a** | pg/ml | 0.0% | 0.8 (0.0–3.1) | 2.7 (0–7.5) | <0.001* | 0.601 (0.542–0.660) |
| MIP-1b** | pg/ml | 0.0% | 52.1 (29.7–82.5) | 72.05 (43.6–134.7) | <0.001* | 0.615 (0.557–0.673) |
*significant after applying the Bonferroni-Holm correction; CRP = C-reactive protein, LBP = lipopolysaccharide binding protein, PCT = procalcitonin; IL-6 = interleukin-6, Fib = fibrinogen according to Clauss, SI = serum iron, TP = total protein, ALAT = alanine transaminase, Alb = albumin, Bili = bilirubin, γ-GT = gamma-glutamyl transpeptidase, Crea = creatinine, LDH = lactate dehydrogenase, Hb = haemoglobin, Plt = platelets, WBC = white blood cell counts, NeuR = relative proportion of neutrophils, EosR = relative proportion of eosinophils, IL-10 = interleukin-10, IL-17a = interleukin-17a, MIP-1b = macrophage inflammatory protein-1β, **not in routine use.