Table 1.
Baseline Characteristics by Mitochondrial DNA Haplogroups
| Mitochondrial DNA Haplogroups | |||||||
|---|---|---|---|---|---|---|---|
| Characteristic | Overall | H | J | T | Uk | Others | P Valuea |
| Overall, N (%) | 455 | 188 (41.3) | 44 (9.7) | 53 (11.7) | 108 (23.7) | 62 (13.6) | … |
| Age, median (IQR), year | 50 (50–54) | 50 (50–53) | 51 (50–54.5) | 50 (50–54) | 50.5 (50–54) | 52 (50–54) | .11 |
| Have college degree, N (%) | 267 (58.7) | 100 (53.2) | 26 (59.1) | 34 (64.2) | 69 (63.9) | 38 (61.3) | .36 |
| Ever smoke, N (%) | 307 (70.7) | 119 (68.0) | 34 (79.1) | 42 (79.3) | 72 (68.6) | 40 (69.0) | .38 |
| Hepatitis C virus infection, N (%) | 75 (16.5) | 29 (15.4) | 6 (13.6) | 16 (30.2) | 16 (14.8) | 8 (12.9) | .11 |
| CD4 cell count at baseline, median (IQR), cells/µL | 523 (354–727) | 499 (358–689) | 550 (323–795) | 597 (371–819) | 533 (371–743) | 510 (325–689) | .74 |
| Human immunodeficiency virus virally suppressed (<200 copies/mL), N (%) | 316 (69.5) | 129 (68.6) | 28 (63.6) | 39 (73.6) | 72 (66.7) | 48 (77.4) | .49 |
| Peripheral neuropathy, N (%) | 170 (37.4) | 70 (37.2) | 16 (36.4) | 19 (35.8) | 44 (40.7) | 16 (35.6) | .96 |
| Weight, median (IQR), kg | 78.6 (70.8–86.2) | 78.9 (72–85.5) | 79.4 (69.1–91) | 79.5 (70.8–86.6) | 76.3 (69.5–85.3) | 79.8 (71.7–85.3) | .69 |
| Height, median (IQR), m | 1.78 (1.73–1.83) | 1.78 (1.73–1.83) | 1.80 (1.75–1.80) | 1.78 (1.73–1.80) | 1.78 (1.73–1.83) | 1.80 (1.75–1.85) | .17 |
| Ever used thymidine analogues, N (%) | 51 (11.5) | 21 (11.7) | 3 (7.0) | 7 (13.2) | 10 (9.4) | 10 (17.0) | .54 |
| Gait speed, mean (standard deviation), m/s | 1.15 (0.19) | 1.13 (0.17) | 1.07 (0.21) | 1.20 (0.21) | 1.20 (0.23) | 1.19 (0.19) | .29 |
Abbreviation: IQR, interquartile range.
aCategorical variables tested by Fisher exact test; continuous variables tested by Kruskal-Wallis equality-of-populations rank test.