Fig. 2.

ES can rescue the respiratory growth deficiency of yeast mutants of copper metabolism. (A) List of yeast genes and their human orthologs implicated in cellular and mitochondrial copper metabolism and the clinical phenotypes associated with mutations in the human or murine genes. (B) Serially diluted WT cells and the indicated mutants were spotted on YPD, YPGE, and YPGE supplemented with 10 nM of ES. The plates were incubated at 37 °C and allowed to grow for 2 d (YPD) or 2 d and 4 d (YPGE) before imaging.