Skip to main content
. 2018 Jun 15;26(8):2060–2069. doi: 10.1016/j.ymthe.2018.05.017

Figure 3.

Figure 3

IAV and EMAPII Induce Hyperpermeability in Endothelial and/or Epithelial Monolayers

(A) HLMVECs grown to confluence were stimulated with 0.2 and 1 pfu/cell of IAV or 1 pfu/cell of heat-inactivated IAV. (B) HPAECs were stimulated with 0.75 pfu/cell IAV in the presence of 10 μg/mL control IgG or EMAPII mAb. (C) A549 were stimulated with 2 pfu/cell IAV, 40 μg/mL recombinant EMAPII, or their combination. (D) A549 were stimulated with 40 μg/mL recombinant EMAPII (E) in the presence/absence of 9 μM QVD (Q). (E) A549 were stimulated with 2 pfu/cell IAV in the presence of 15 μg/mL control IgG or EMAPII mAb. Shown are mean ± SE of three parallel recordings; resistance is normalized to the moment of stimulation with IAV/EMAPII (shown with an arrow in A and B). *p < 0.05 by t test.