Figure 4.

Self-Limiting IAV Infection in Mice Is Accompanied by Lung Injury

Mice were administered 750 pfu/mouse IAV to lung and analyzed for (A) weight loss, (B) conscious blood oxygenation, (C) lung edema, (D) BALF protein extravasation, and (E) BALF white blood cell (WBC) count including total WBC (t), macrophages (m), lymphocytes (l), and neutrophils (n). (A and B) n = 5, (C and D) n = 7 for control group and 3 or 4 for all other groups; data are presented as mean ± SEM. *p < 0.05 by ANOVA with Tukey post-hoc when compared to control values.