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. 2018 Summer;17(3):995–1007.

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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PFOS-induced cellular proteolysis in human lymphocytes.Cellular proteolysis after treatment of human lymphocytes with PFOS. Cellular proteolysis was assessed based on reaction of OPA with amino groups in presence of 2-mercaptoethanol. Statistically significant (P < 0.05) increase in free amino acids was observed at highest concentration of PFOS (300 µM) at all of time intervals, but 150 µM PFOS induced significant (P < 0.05) release of amino acids only at 4 and 6 h after treatment in comparison with control. ^*P < 0.05, ^**P < 0.01 and ^***P < 0.001.