Table 4.
Results of droplet size, PDI and drug content analysis of nanoemulsions, stored at various temperatures at the end of 9 and 12 months
| Formulation |
4 °C
|
25 C
|
40 C
|
Drug content (%)
|
|||
|---|---|---|---|---|---|---|---|
| Size (nm) | PDI | Size (nm) | PDI | Size (nm) | 4 C * | 25 C ** | |
| F56 | 44.4 ± 0.8 | 0.223 | 39.7 ± 0.68 | 0.360 | phase separation | 80.8 ± 0.44 | 4.47 ± 2.41 |
| F87 | 41.9 ± 1.25 | 0.376 | 48.1 ± 1.15 | 0.203 | phase separation | 75.5 ± 2.67 | 6.94 ± 0.03 |
| F98 | 45.3 ± 0.55 | 0.291 | 45.3 ± 0.26 | 0.233 | 79.2 ± 3.87 | 88.5 ± 0.24 | 52.94 ± 0.11 |
| F125 | 101.2 ± 4.55 | 0.354 | 96.5 ± 1.36 | 0.269 | 137.8 ± 2.36 | 77.2 ± 0.61 | 57.54 ± 0.18 |
*
9-month storage,
**
12-month storage.