Table 3.
Effect of surfactants and cholesterol on size, zeta potential and EE% of phytoniosomes.
|
Formulation
ID |
Surfactants molar ratio
|
Size (µm) ± SD |
Zeta potential
(mV) ± SD |
EE% ± SD | ||||
|---|---|---|---|---|---|---|---|---|
| Span 40 | Tween 40 | Span 60 | Tween 60 | Cholesterol | ||||
| F1 | 3.5 | 3.5 | ˗ | ˗ | 3 | 6.19±0.43 | 26.39±1.08 | 45.4±3.8 |
| F2 | 3 | 3 | ˗ | ˗ | 4 | 5.59±0.37 | 26.95±1.76 | 67.4±4.3 |
| F3 | 2.5 | 2.5 | ˗ | ˗ | 5 | 15.87±2.27 | 4.15±0.33 | 60.1±4.1 |
| F4 | ˗ | ˗ | 3.5 | 3.5 | 3 | 5.28±0.31 | 25.33±1.40 | 90.8±4.6 |
| F5 | ˗ | ˗ | 3 | 3 | 4 | 7.29±0.47 | 25.66±2.19 | 91.5±5.3 |
| F6 | ˗ | ˗ | 2.5 | 2.5 | 5 | 8.60±0.60 | 24.52±1.98 | 93.4±3.3 |
EE% entrapment efficiency percent.