Figure 3.

Relaxation effect of saffron aqueous extract in endothelium-intact aortic rings in non-incubated and incubated tissues with L-NAME (10-6 M) for 20 min. Then aortic rings were contracted by 10⁻⁶ M PE and the vasorelaxant effect of saffron was then examined. Values are expressed as mean ± SEM. ^*P < 0.05 and ^***P < 0.001 vs. L-NAME preincubated rings. PE: phenylephrine