Table 4.
Comparison of maternal and newborn adverse events between the three groups
| Adverse event | Normal saline (n = 72) | Ondansetron 0.05 mg/kg (n = 71) |
Ondansetron 0.1 mg/kg (n = 72) |
P-value |
|---|---|---|---|---|
| Mother | ||||
| Urticaria | 1 (1.4) | 0 (0) | 2 (2.8) | 0.78 |
| Arrhythmia | 2 (2.8) | 0 (0) | 1 (1.4) | 0.78 |
| Vomiting | 10 (13.9) | 10 (14.1) | 3 (4.2) | 0.09 |
| Itching | 10 (13.9) | 4 (5.6) | 7 (9.7) | 0.25 |
| Newborn | ||||
| Apgar 1, median (IQR) | 9 (8–9) | 9 (8–9) | 9 (8–9) | 0.94 |
| Apgar 5, median (IQR) | 9 (9–9) | 9 (9–9) | 9 (9–9) | 0.14 |
| Hypotension | 0 (0) | 1 (1.4) | 0 (0) | 0.33 |
| Tachypnea | 2 (2.8) | 5 (7.0) | 0 (0) | 0.04* |
Data are presented as frequency (%) unless stated otherwise
*no differences for multiple comparisons between groups (P > 0.05)