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. 2017 Oct 4;4(3):161–167. doi: 10.2217/mmt-2017-0014

Table 4. . Outcomes of ipilimumab-treated patients who received pembrolizumab.

Pt# Best response to ipilimumab Time (days) between PD and pembrolizumab Best response to pembrolizumab Total cycles received PFS (months) OS (months)
1 PD 29 PR 41, ceased due to PD 36.9 44.7

2 PD 187 CR 33, ceased due to CR/AE NR, 47.4+ NR, 47.4+

9 PD 15 PD 4, ceased due to PD 2.3 5.3

10 PR 34 PD 2, ceased due to PD 1.8 3.9

12 Not assessed 21 (planned switch) PD 3 3.2 9.6

13 PD 39 SD 20+, ongoing NR, 13.5+ NR, 13.5+

From time of initiating pembrolizumab.

This patient received chemotherapy with four cycles of carboplatin/paclitaxel and had a sustained PR of 5 months.

AE: Adverse event; CR: Complete response; NR: Not reached; OS: Overall survival; PD: Progressive disease; PFS: Progression-free survival; PR: Partial response; Pt#: Patient number; SD: Stable disease.