Table 1. . Studies showing a link between 25(OH)D level and markers of melanoma prognosis.
Study (year) | Measure of prognosis | Sampling of 25(OH)D | Outcome | Ref. |
---|---|---|---|---|
Randerson-Moor et al. (2009) | Breslow thickness | At least 3–6 months after diagnosis | Inverse correlation between 25(OH)D level and Breslow thickness | [90] |
Gambichler et al. (2013) | Breslow thickness | At baseline (up to 6 months after diagnosis) and 6 months later | Lower Breslow thickness was a predictor of high 25(OH)D concentration | [91] |
Nurnberg et al. (2009) | CMM stage at diagnosis | Sampling between October and April (time between diagnosis and sampling highly variable) | Serum 25(OH)D levels significantly lower in stage IV vs stage 1 CMM | [92] |
Newton-Bishop et al. 2009 | Breslow thickness; relapse-free survival | Sampling 3–6 months after diagnosis | Significant trend toward lower 25(OH)D levels in association with higher Breslow thickness and lower relapse-free survival | [93] |
25(OH)D: 25 hydroxyvitamin D; CMM: Cutaneous malignant melanoma.