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. 2015 Feb 25;2(1):51–61. doi: 10.2217/mmt.14.31

Table 1. . Studies showing a link between 25(OH)D level and markers of melanoma prognosis.

Study (year) Measure of prognosis Sampling of 25(OH)D Outcome Ref.
Randerson-Moor et al. (2009) Breslow thickness At least 3–6 months after diagnosis Inverse correlation between 25(OH)D level and Breslow thickness [90]

Gambichler et al. (2013) Breslow thickness At baseline (up to 6 months after diagnosis) and 6 months later Lower Breslow thickness was a predictor of high 25(OH)D concentration [91]

Nurnberg et al. (2009) CMM stage at diagnosis Sampling between October and April (time between diagnosis and sampling highly variable) Serum 25(OH)D levels significantly lower in stage IV vs stage 1 CMM [92]

Newton-Bishop et al. 2009 Breslow thickness; relapse-free survival Sampling 3–6 months after diagnosis Significant trend toward lower 25(OH)D levels in association with higher Breslow thickness and lower relapse-free survival [93]

25(OH)D: 25 hydroxyvitamin D; CMM: Cutaneous malignant melanoma.