Table 2.

Top 25 up-regulated genes in IPF vs. NSIP (SAM analysis)

NCBI Gene Symbol	NCBI Gene name	d	Fold change vs. NSIP group	q value
IGFBP5	insulin like growth factor binding protein 5	4.70	1.78	< 0.0001
SLN	sarcolipin	4.69	2.57	< 0.0001
SYNPO2	synaptopodin 2	4.61	2.08	< 0.0001
MYH11	myosin, heavy chain 11, smooth muscle	4.38	1.99	< 0.0001
DES	desmin	4.33	2.05	< 0.0001
NLGN4Y	neuroligin 4, Y-linked	4.24	2.55	< 0.0001
FAM83D	family with sequence similarity 83, member D	4.23	1.65	< 0.0001
ACTG2	actin, gamma 2, smooth muscle, enteric	4.16	2.25	< 0.0001
TPM2	tropomyosin 2 (beta)	4.13	1.62	< 0.0001
CNN1	calponin 1, basic, smooth muscle	4.06	1.77	< 0.0001
PRUNE2	prune homolog 2 (Drosophila)	4.01	1.84	< 0.0001
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	4.00	7.99	< 0.0001
RPS4Y1	ribosomal protein S4, Y-linked 1	4.00	7.25	< 0.0001
AHNAK2	AHNAK nucleoprotein 2	3.93	1.76	< 0.0001
DDX3Y	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked	3.91	11.4	< 0.0001
KDM5D	lysine (K)-specific demethylase 5D	3.89	5.23	< 0.0001
TXLNGY	taxilin gamma pseudogene, Y-linked	3.89	7.08	< 0.0001
ATP1A2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	3.87	1.66	< 0.0001
ACTA-2	actin, alpha 2, smooth muscle, aorta	3.87	1.51	< 0.0001
TXLNGY	taxilin gamma pseudogene, Y-linked	3.86	5.71	< 0.0001
ZFY	zinc finger protein, Y-linked	3.79	4.13	< 0.0001
PDLIM3	PDZ and LIM domain 3	3.79	1.55	< 0.0001
TAGLN	transgelin	3.77	1.60	< 0.0001
UTY	ubiquitously transcribed tetratricopeptide repeat	3.72	7.80	< 0.0001
IGFBP6	insulin like growth factor binding protein 6	3.66	1.60	< 0.0001