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. 2018 Aug 15;9:28. doi: 10.1186/s13100-018-0133-4

Fig. 1.

Fig. 1

AMH-specific RIs, genes and preferential expression. a Proportion of ENSEMBL-annotated genes in the whole reference genome GRCh37-hg19 (grey), proportion of insertions that occurred in annotated genes for RT-DB insertions (yellow), AMH-specific RI vs chimp (blue) and AMH-specific RI vs both HN and HD (red). In each diagram, the darker color denotes the percentage of RIs inserted in genes vs RIs inserted in non-genic regions (lighter color). b Proportion of genes per number of annotated transcripts for all ENSEMBL-annotated genes in the reference genome GRCh37-hg19 (black dotted line), for genes with RT-DB insertions (yellow lines), for genes containing AMH-specific RIs vs chimp (blue bars) and for genes with AMH-specific RIs vs both HN and HD (red bars). c Table showing statistical significance of the differences between the series of Fig. 3B, calculated with Kolmogorov-Smirnov tests; white is for non-significant p-value, light-green is for p-value < 10− 2, pea-green is for p-value < 10− 5, emerald-green is for p-value < 10− 10, dark-green is for p-values < 10− 16. d Proportion of all human genes showing preferential expression in different tissues (grey bars); % increase or decrease in absolute proportions for preferential tissue expression of genes with RT-DB insertions (yellow bars), genes containing AMH-specific RIs vs chimp (blue bars) and genes with AMH-specific RIs vs both HN and HD (red bars). Black asterisks mark significant differences between the series and all human genes while yellow asterisks mark significant differences between the series and genes that contain RT-DB insertions. e Proportion of all human genes showing preferential expression in the brain divided by neural regions (grey bars); % increase or decrease in absolute proportions for preferential neural expression of genes with RT-DB insertions (yellow bars), genes containing AMH-specific RIs vs chimp (blue bars) and genes with AMH-specific RIs vs both HN and HD (red bars). Black asterisks mark significant differences between the series and all human genes, yellow asterisks mark significant differences between the series and genes containing RT-DB insertions, blue asterisks mark significant differences between the series and genes containing AMH-specific RIs vs chimp