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RAC1 is a direct target of miR-885-5p. (A) The putative complementary site of miR-885-5p and RAC1 was obtained based on TargetScan prediction. (B) The sequences of wild-type RAC1 (RAC1-3′-UTR-WT), mutant-type RAC1 (RAC1-3′-UTR-Mut), and miR-885-5p are shown. (C) TPC-1 cells were transfected with scramble or miR-885-5ps, RAC1-3′-UTR-WT or RAC1-3′-UTR-Mut, respectively. The luciferase intensity was measured by dual-luciferase reporter assay (* P<0.05).
