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. 2018 Aug 7;24:5488–5500. doi: 10.12659/MSM.911095

Figure 6.

Figure 6

Silencing RAC1 suppressed PTC cell proliferation. (A) The relative expression level of RAC1 was analyzed by qRT-PCR assay in K1 and TPC-1 cells transfected with si-circ_0004458 or anti-miR-885-5p, respectively (* P<0.05). (B, C) Cell viability was detected by MTT assay in K1 and TPC-1 cells transfected with si-control or si-RAC1, respectively (* P<0.05). (D) The cell clonogenesis ability was accessed by clone formation assay in K1 and TPC-1 cells transfected with si-control or si-RAC1, respectively (* P<0.05). (E) The schematic representation of circ_0004458/miR-885-5p/RAC1 in PTC cells.