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. 2018 Aug 9;9:912. doi: 10.3389/fphar.2018.00912

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Copyright © 2018 Li, Luo, Hu, Guo, Yang, Zhang and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cyclocarya paliurus leaves (CPAE) improves lipid metabolism disorders, reduces hepatic steatosis, attenuates liver injury and improves diabetic nephropathy. (A) Levels of FFA, TG, TC and HDL-c/LDL-c in the serum (n = 6). (B) Histopathological examination of liver tissues (magnification, 200×) (n = 3). The scale bar is 40 μm. (C) Levels of serum ALT and AST (n = 6). (D) Histopathological examination of kidney tissues (H&E staining) (magnification, 200×) and thickness of glomerular basement membrane (n = 3). The scale bar is 40 μm. (E) Levels of serum BUN and Cre (n = 6). ^∗p < 0.05, ^∗∗p < 0.001, ^∗∗∗p < 0.0001.