Table 1.
Association of miR-421 with clinicopathological features of NSCLC patients
| Features | All cases | miR-421 expression
|
P | |
|---|---|---|---|---|
| Low | High | |||
| Total | 132 | 61 | 71 | |
| Age (years) | 0.816 | |||
| ≤60 | 57 | 27 | 30 | |
| >60 | 75 | 34 | 41 | |
| Gender | 0.857 | |||
| Female | 53 | 25 | 28 | |
| Male | 79 | 36 | 43 | |
| Smoking history | 0.112 | |||
| No | 51 | 28 | 23 | |
| Yes | 81 | 33 | 48 | |
| Tumor size (cm) | 0.145 | |||
| ≤3 | 56 | 30 | 26 | |
| >3 | 76 | 31 | 45 | |
| Lymph-node metastasis | 0.008 | |||
| Negative | 53 | 32 | 21 | |
| Positive | 79 | 29 | 50 | |
| Differentiation | 0.339 | |||
| Good/moderate | 83 | 41 | 42 | |
| Poor | 49 | 20 | 29 | |
| TNM stage | 0.004 | |||
| I–II | 58 | 35 | 23 | |
| III–IV | 74 | 26 | 48 | |
Note: P<0.05 are shown in bold.
Abbreviations: miR-421, microRNA-421; NSCLC, non-small-cell lung cancer.