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. 2018 Aug 13;13:4641–4659. doi: 10.2147/IJN.S166584

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© 2018 Wang et al. This work is published and licensed by Dove Medical Press Limited

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Characteristics of PG.

Notes: (A) ¹H NMR spectra in D₂O: GQ8 (a), P123 (b), PG (c). (B) MALDI-TOF MS: P123 (a), PG (b). (C) Plot of UV absorption of I₂ versus concentration of P123 and PG. When absorbance increased dramatically, the corresponding concentration was the CMC of PG. Values expressed as means (n=3). (D) Western blotting analysis of Pgp expression in B16F10 cells after incubation with P123 and PG at various concentrations.

Abbreviations: P123, Pluronic P123; GQ8, GPLGIAGQ-NH₂ peptide; PG, P123 modified with GQ8; NMR, nuclear magnetic resonance; MALDI-TOF MS, matrix-assisted laser desorption–ionization time-of-flight mass spectrometry; CMC, critical micelle concentration.