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. 2018 Aug 13;13:4641–4659. doi: 10.2147/IJN.S166584

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© 2018 Wang et al. This work is published and licensed by Dove Medical Press Limited

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Biodistribution of intravenous injection and inhalation of micelles in rats.

Notes: (A) Dissected organs of rats killed at 1, 6, and 12 hours after inhalation and intravenous injection of DiR-labeled P123 micelles; (B) distribution of DiR in the lung after inhalation of DiR-labeled P123 micelles; (C) ratio of fluorescence intensity in the lung to all organs (heart, liver, spleen, lung, and kidney) after inhalation and intravenous injection of DiR-labeled P123 micelles; (D) fluorescence intensity in the lung after inhalation and intravenous injection of DiR-labeled P123 micelles. ^***P<0.001 compared with inhalation. Values expressed as means ± SD (n=3).

Abbreviation: P123, Pluronic P123.