Table 1. . WHO classification and grading (2010) of gastro-entero-pancreatic neuroendocrine neoplasms.
| Mitotic count | Ki67 index | ||||
|---|---|---|---|---|---|
| Neuroendocrine tumor | Low grade | G1 | <2 mitoses/hpf | ≤2% | |
| Intermediate grade | G2 | 2–20 mitoses/hpf | 3–20% | ||
| Neuroendocrine carcinoma | High grade | G3 | Small cells or large cells | >20 mitoses/hpf | >20% |
hpf: High power field.
Reproduced with permission from [10].