Table 4.
Results of the linear mixed models evaluating the association between cortisol concentrations at baseline, and 60 min after ACTH administration with the presence of EGGD, ESGD, and horse characteristics in two different horse populations (SHP and GP)
| Model | Variable | Parameter estimate | Standard error | P-value |
|---|---|---|---|---|
| Baseline cortisol in SHP | EGGD: | |||
| EGGD (reference: No) | - | - | - | |
| EGGD yes | −0.3375 | 0.16872 | 0.0569 | |
| Baseline cortisol in GP | Breed: | |||
| Warmblood (reference) | - | - | - | |
| Franches-Montagnes | −0.07293 | 0.09036 | 0.42314 | |
| Pony | −0.29398 | 0.08999 | 0.00189 | |
| Other | −0.14056 | 0.06319 | 0.03032 | |
| Clinical signs: | ||||
| Healthy (reference) | - | - | - | |
| Recurrent colic episodes | 0.23698 | 0.07855 | 0.00389 | |
| Acute colic | 0.17442 | 0.07486 | 0.02357 | |
| Weight loss | −0.04985 | 0.10072 | 0.62264 | |
| Other gastrointestinal signs | 0.17906 | 0.09956 | 0.07769 | |
| Cortisol 60 min after ACTH stimulation in SHP | EGGD: | |||
| EGGD (reference: No) | - | - | - | |
| EGGD yes | 2.52 | 0.6839 | 0.00116 | |
| Cortisol 60 min after ACTH stimulation in GP | EGGD: | |||
| EGGD (reference: No) | - | - | - | |
| EGGD yes | 0.3325 | 0.16973 | 0.0548 | |
ACTH = adrenocorticotropic hormone; EGGD = equine glandular gastric disease; ESGD = equine squamous gastric disease; GP = the general population; SHP = sport horse population