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. 2014 Mar 20;1(2):205–214. doi: 10.2217/hep.13.18

Table 1. Results of local response and survival in recent studies.

Study (year) Local response (%) Survival (%) Comment Ref.
Varela et al. (2007) Response: 66
PR: 44.4
SD: 25.9
CR: 25.9
At 12 months: 92.5
At 24 months: 88.9
On intention-to-treat [4]

Poon et al. (2007) CR: 6.7
PR: 63.3
At 12 months: 92.5
At 24 months: 88.9
Prospective study
Results at 1 month
[5]

Malagari et al. (2008) CR: 12.2
PR: 75.6
PD: 6.8
SD: 12.2
NA At 9 months after three scheduled sessions
Prospective study
[15]

Malagari et al. (2008) CR: 16.1
OR: 72
At 18 months: 94.1
At 30 months: 88.2
After three scheduled sessions
Prospective study
[16]

Kettenbach et al. (2008) CR: 27
PR: 13
PD: 40
SD: 3
At 6 months: 93 Prospective study [17]

Sacco et al. (2011) CR: 51.5§
PR: 48.5§
PD: 17.9
At 24 months estimated: 86.8 Prospective–randomized study [18]

Sycha et al. (2012) OR: 89% NA NA [20]

Dhanasekaran et al. (2010) NA At 6 months: 71
At 12 months: 58
At 24 months: 48
Median survival 610 days§
Retrograde study [22]

Lammer et al. (2010) CR: 27§
OR: 52§
DC: 63§
NA Prospective–randomized study [24]

Malagari et al. (2012) CR: 22.5–23.5
PR: 46.5–49
PD: 8.4–4.9
SD: 22.5
At 12 months: 93.6
At 24 months: 83.8
At 3 years: 62.0
At 4 years: 41.0
At 5 years: 22.5
Mean overall survival: 43.8 months
Prospective study
After three scheduled sessions and then on demand
[27]

Burrel et al. (2012) NA Median survival after
censoring at the time of transplant/sorafenib was 47.7 months
Prospective study [28]

Response Evaluation Criteria In Solid Tumors criteria.

WHO-modified criteria.

§In the DC Bead™ arm.

Range for Child–Pugh A and Child–Pugh B cirrhosis.

CR: Complete response; DC: Disease control (complete response plus partial response plus stable disease); NA: Not applicable; OR: Objective response (complete response plus partial response); PD: Progressive disease; PR: Partial response; SD: Stable disease.