. 2017 Jan 20;3(4):223–239. doi: 10.2217/hep-2016-0009

Table 1. . The seventh edition of American Joint Committee on Cancer/Tumor Node Metastasis staging system for intrahepatic bile duct tumors.

*Primary tumor (T)*

TX	Primary tumor cannot be assessed

T0	No evidence of primary tumor

Tis	Carcinoma in situ (intraductal tumor)

T1	Solitary tumor without vascular invasion

T2a	Solitary tumor with vascular invasion

T2b	Multiple tumors, with or without vascular invasion

T3	Tumor perforating the visceral peritoneum or involving the local extra hepatic structures by direct invasion T4 tumor with periductal invasion

*Regional lymph nodes (N)*

NX	Regional lymph nodes cannot be assessed N0 No regional lymph node metastasis

N1	Regional lymph node metastasis present

*Distant metastasis (M)*

M0	No distant metastasis

M1	Distant metastasis present

*Anatomic stage groupings*

Stage 0	Tis	N0	M0

Stage I	T1	N0	M0

Stage II	T2	N0	M0

Stage III	T3	N0	M0

Stage IVA	T4	N0	M0
	Any T	N1	M0

Stage IVB	Any T	Any N	M1