Table 3. . Detection of primary hepatocellular carcinoma by various PET tracers.
| Study (year) | PET | HCC appearance | Sensitivity (%) | Specificity (%) | Ref. |
|---|---|---|---|---|---|
| Wudel et al. (2003) | 18F-FDG | High uptake in poorly differentiated HCC, no significant uptake in well-differentiated HCC, background uptake in liver parenchyma | 64 | – | [89] |
| Park et al. (2008) | 11C-acetate | High uptake in well-differentiated HCC, background uptake in liver parenchyma | 75 | [90] | |
| Talbot et al. (2010) | 18F-choline | Increased uptake in well-differentiated HCC, low uptake in poorly differentiated HCC, high background uptake in liver parenchyma | 88 | 62 | [91] |
| Talbot et al. (2010) | 18F-FDG + 11F-choline | 94 | – | [91] | |
| Park et al. (2008) | 18F-FDG + 11C-acetate | 86 | – | [90] | |
HCC: Hepatocellular carcinoma.