Table 1. . miRNA biomarkers in human hepatocellular carcinoma.
| Types of biomarkers | miRNAs | Ref. |
|---|---|---|
| HCV tumor vs nontumor | 29 miRNAs (miR-10, miR-100, miR-198 and miR-145, among others) | [17] |
| Benign vs malignant | 6 miRNAs (miR-200c, miR-203, miR-21, miR-10b, miR-222 and miR-224, among others) | [14] |
| HpSC- vs MH-HCC | DLK1-DIO miRNA cluster on chromosome 14q32.2 | [7] |
| 20 miRNAs (miR-181 family, and so on) | [28] | |
| HBV- vs HCV-related HCC | 19 miRNAs (miR-190, miR-134, miR-151, miR-193, miR-133b, miR-324-5p, miR-182*, miR-105, miR-211, miR-20, miR-191, miR-340, miR-194, miR-23a, miR-142-5p, miR-34c, miR-124b, let-7a and miR-27a) | [15] |
| Survival | DLK1-DIO3 miRNA cluster | [7] |
| Metastasis | 20 miRNAs (miR-338, miR-219-1, miR-207, miR-185, miR-30c-1, miR-1-2, miR-34a, miR-19a, miR-148a, miR-124a-2, miR-9-2, miR-148b, miR-122a, miR-125b-2, miR-194, miR-30a, miR-126, let-7g, miR-15a and miR-30e) | [38] |
| Drug response/resistence | miR-26 | [44] |
| miR-122 | [41] | |
| Diagnosis | miR-15b and miR130b | [32] |
| miR-16 | [34] | |
| miR-122, miR-192, miR-21, miR-223, miR-26a, miR-27a and miR-801 | [35] | |
| miR-21 | ||
HBV: Hepatitis B virus; HCC: Hepatocellular carcinoma; HCV: Hepatitis C virus; HpSC: Hepatic stem cell-like; MH: Mature hepatocyte-like.