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. Author manuscript; available in PMC: 2018 Oct 11.
Published in final edited form as: Nature. 2018 Apr 11;556(7701):370–375. doi: 10.1038/s41586-018-0035-0

Extended Data Figure 4. Aspm KO mice do not demonstrate displaced progenitors in the IZ.

Extended Data Figure 4

Unlike Aspm−/− ferrets, Aspm−/− mice do not demonstrate displaced NPC in the IZ. However, they show a variable increase in IP (Pax6-/Ki67+ cells in a and Tbr2+ cells in b), which is enhanced by heterozygous, compound mutation in Wdr62, a microcephaly gene causing more severe microcephaly9. The experiments were repeated 3 times independently with similar results. Scale bar: 100 μm.