Table 4.

Unadjusted univariate and adjusted multivariable stepwise forward logistic regression model of the odds of an asymptomatic intracranial hemorrhage at or before the 24 h unenhanced head CT. Results were adjusted for baseline covariates available at the time of enrollment that were significant at the p<0.10 level in univariate logistic regression.

Covariate	Unadjusted OR (95% CI)	p-value	Adjusted OR (95% CI)	p-value
Symptom Discovery to alteplase, h	0.42 (0.21, 0.87)	0.02	0.58 (0.24, 1.42)	0.23
History of Atrial Fibrillation	7.26 (2.37, 22.23)	<0.001	3.20 (0.80, 12.77)	0.099
Initial INR	711.17 (2.64, >999)	0.02	4.56 (0.003, >999)	0.68
Initial NIHSS	1.28 (1.14, 1.43)	<0.001	1.22 (1.08, 1.38)	0.001

Time interval OR are per hour, NIHSS and INR are per point. OR, Odds Ratio; NIHSS, NIH stroke scale; mRS, modified Rankin Scale.

^*Lacunar subtype was not included in final multivariable analyses since there were no subjects with lacunar subtype who had AICH, resulting in an unstable fit.