. 2018 Aug 16;13(8):e0198307. doi: 10.1371/journal.pone.0198307

Table 1. Changes in hemodynamic parameters (means ± SD) in diabetic rats.

MAP	D-Sham	D-IRC	DEX^pre	DEX^post
Baseline	90.2 ± 17.7	89.4 ± 9.6	96.3 ± 12.2	90.7 ± 7.0
During ischemia		84.7 ± 23.1	81.1 ± 5.1	73.9 ± 11.0
After reperfusion		120.6 ± 7.4^*	123.2 ± 8.1^*	114.1 ± 4.4^*^,^‡
HR	D-Sham	D-IRC	DEX^pre	DEX^post
Baseline	269.3 ± 20.8	281 ± 25.9	314.5 ± 99.7	265.4 ± 23.8
During ischemia		254.1 ± 71.7	230.0 ± 49.7	238.5 ± 29.8
After reperfusion		312.1 ± 26.8^*	263.6 ± 30.5^†	257.9 ± 27.1^†

MAP and HR were recorded 15 min after starting intraperitoneal anesthesia (baseline), 45 min after inducing ischemia (during ischemia), and after 24-h reperfusion (after reperfusion).

MAP: mean arterial blood pressure; HR: heart rate; DEX: dexmedetomidine; D-IRC: diabetic ischemia-reperfusion control.

*p < 0.05, compared with the sham baseline

†p < 0.05, compared with D-IRC group

‡p < 0.05, compared with DEX pre-treatment group