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. 2018 Aug 16;13(8):e0202497. doi: 10.1371/journal.pone.0202497

Table 1. Characteristics of studies included in the review, measuring the association between passive exposure to tobacco use and the presence of caries in children and adolescents.

Study Type n Age(yr) Exposure Dentition Outcome Association
Aida et al., 2008[14] CS 3086 3 Postnatal Primary OR = 2.14 (1.59–2.87) Yes
Aligne et al., 2003[15] CS 3531 4 to 11 Postnatal Primary a: OR = 1.8 (1.2–2.7); ds Yes
Permanent b: OR = 1.2 (0.8–1.85); DS No
Almerich et al., 2013[16] CS 889 12 Postnatal Permanent a: OR = 1.2 (0.82–1.75) No
15 Permanent b: OR = 1.24 (0.84–1.83)
Avçar et al., 2008[35] CC 90 5 Postnatal Primary Cases: dft = 10.58±2.12 Yes
90 Controls: dft = 4.64±2.91
Ayo-Yusuf et al., 2007[17] CS 1873 13 to 15 Postnatal Permanent Caries in 2nd molars Yes
OR = 2.02 (1.22–3.33)
Bakhurji et al., 2017 [33] CS 294 12–15 Postnatal Permanent OR = 1.37 (0.46–4.08) No
Bernabé et al., 2017[36] L 1102 1–4 Postnatal Primary Data 4 years; Exposed dmfs = 5.18±9 Yes
Non-exposed dmfs = 2.78 ±6.51
Carbajosa et al., 2011[18] CS 380 10 to 15 Postnatal Permanent Exposed DMFT = 1.62±2.2; df = 0.27±0.78 Yes
Non-exposed DMFT = 0.92±1.40; df = 0.10±0.47
Claudia et al., 2016 [41] L 1687 0.5–6 Prenatal Primary RR = 1.42 (1.20–1.68) Yes
Ditmyer et al. 2010[19] CS 4169 12 to 19 Postnatal Permanent Highest DMFT group Yes
OR = 1.42 (1.03–1.53)
Exposed DMFT = 7.23±0.06
Non-exposed DMFT = 6.74±0.10
Hanioka et al., 2008[20] CS 711 3 Postnatal Primary OR = 2.25 (1.51–3.37) Yes
Exposed dt = 2.1 (1.7–2.5)
Non-exposed dt = 1.2 (0.8–1.6)
Iida et al., 2007[21] CS 1576 2 to 5 Prenatal Primary OR: 1.68 (1.01–2.79) Yes
Julihn et al., 2009[37] L 15538 13 to 19 Postnatal Permanent Interproximal caries Yes
OR = 1.33 (1.22–1.44)
Leroy et al., 2008[22] CS 2533 3 Postnatal Primary a: OR = 1.98 (0.68–5.76) Yes
5 Postnatal Primary b: OR = 3.36 (1.49–7.58)
Majorana et al., 2014[23] CS 2395 2–3 Postnatal Primary Severe caries Yes
OR = 1.62 (1.34–1.96)
Nakayama et al., 2015[24] CS 1801 3 Postnatal Primary OR = 1.91 (1.43–2.54) Yes
Exposed dfs = 1.27±2.98
Non-exposed dfs = 0.53±1.69
Nayani et al., 2018 [34] CS 500 5–14 Postnatal Permanent Prevalence ratio <30min = 1.25 (1.07–1.45) Yes
Prevalence ratio >30min = 1.34 (1.05–1.35)
Pita-Fernández et al., 2011[25] CS 281 6 to 10 Postnatal Primary a: OR = 1.12 (0.55–2.28) No
Postnatal Permanent b: OR = 1.47 (0.62–3.47)
Plonka et al., 2012[38] L 1017 2–3 Postnatal Primary Predictive variable in a logistic model Yes
Shenkin et al., 2004[39] L 637 4 to 7 Postnatal Primary OR = 3.38 (1.68–6.79) Yes
Shulman et al. 2005[26] CS 7779 2 to 6 Postnatal Primary Exposed dft = 3.19 (1.03) No
Non-exposed dft = 2.10 (0.17)
Tanaka et al., 2006[27] CS 925 1 to 14 Postnatal Primary OR = 1.26 (0.93–1.69) No
Tanaka et al., 2009[28] CS 2015 3 Prenatal Primary a: OR = 1.43 (1.07–1.91) Yes
Postnatal b: OR = 1.25 (1.04–1.50)
Tanaka et al., 2010[29] CS 20703 6 to 15 Postnatal Permanent OR = 1.29 (1.24–1.34) Yes
Tanaka K et al., 2015[30] CS 6412 3 Prenatal Primary a: OR = 1.70 (1.15–2.48) Yes
Postnatal Primary b: OR = 1.23 (1.05–1.45)
Tanaka S et al., 2015[40] RC 76920 3 Prenatal Primary a: HR = 1.46 (1.40–1.52) Yes
Postnatal Primary b: HR = 2.14 (1.99–2.29)
Wiener et al., 2013[31] CS 91642 1–15 Postnatal Permanent Special health care needs children Yes
OR = 1.23 (1.02–1.50)
Williams et al., 2000[32] CS 749 3 to 15 Postnatal Primary OR: 1.54 (1.07–2.21) Yes

RC: retrospective cohorts; CS: cross-sectional; CC: case controls; L: longitudinal; OR: odds ratio; HR: hazard ratio; DMFT: permanent teeth decayed, missing and filled; DS: permanent tooth surfaces decayed; ds: primary tooth surfaces decayed; dft: primary teeth decayed and filled; dfs: primary tooth surfaces decayed and filled.