Fig 4. Differential regulation of 4 peptides in the CSF of patients with relapsing and progressive MS.
Level of peptides relative to the respective stable isotope standard is indicated by scatter plots, and was quantified by targeted proteomics, parallel reaction monitoring in the CSF of patients with relapsing-remitting MS (RRMS, n = 40), secondary progressive MS (SPMS, n = 27), and primary progressive MS (PPMS, n = 30). (ANOVA, corrected for multiple-testing, using Benjamini-Hochberg). See also S1 and S3 Tables.