. Author manuscript; available in PMC: 2018 Aug 16.

Published in final edited form as: Arch Phys Med Rehabil. 2016 Mar 2;97(8):1295–1300.e4. doi: 10.1016/j.apmr.2016.02.009

Table 3.

List of improbable CRS-R subscore combinations.

Improbable subscore combinations
Subscore 1	Subscore 2	Possible contributing factors (when scoring errors are ruled out)
No auditory response (A0)⁺	Functional object use (M6)⁺	Deafness
No auditory response (A0)⁺	Attention (Ar3)⁺	Deafness
Auditory startle (A1)⁺	Functional object use (M6)⁺	Aphasia; Central deafness
Localization to sound (A2)⁺	Attention (Ar3)⁺	Aphasia; Central deafness
Consistent command following (A4)⁺	Visual startle (V1) ⁺	3^rd and 4^th cranial nerve palsy; Ocular apraxia; Visual agnosia
Consistent command following (A4)⁺	Abnormal posturing (M1)⁺	Severe spasticity
Consistent command following (A4)⁺	Unarousable/No eye-opening (Ar0)⁺	Bilateral ptosis^‡; Facial oedema^‡; Eyelid apraxia^‡
Blink to threat (V1)⁺	Functional object use (M6)⁺	Bilateral optic nerve damage; Terson’s syndrome; Cortical blindness
Blink to threat (V1)⁺	Functional communication (C2)⁺
Visual fixation (V2)⁺	Unarousable (Ar0)⁺	Ptosis^‡; Eyelid apraxia^‡
Object localization (V4)⁺	Unarousable (Ar0)⁺	Ptosis^‡; Eyelid apraxia^‡
Object localization (V4)⁺	No motor response (M0)⁺
Object recognition (V5)⁺	Abnormal posturing (M1)⁺	Severe spasticity
Object recognition (V5)⁺	Unarousable (Ar0)⁺	Ptosis^‡; Eyelid apraxia^‡
Abnormal posturing (M1)⁺	Intelligible verbalization (Ve3)⁺	Severe spasticity
Functional object use (M6)⁺	Unarousable (Ar0)⁺	Ptosis^‡; Eyelid apraxia^‡
Functional communication (C2)⁺	Unarousable (Ar0)⁺	Ptosis^‡; Eyelid apraxia^‡
Reproducible command following (A3)^†	Functional communication (C2)^†	N/A^*
Consistent command following (A4)^†	No visual response (V0) ^†	Bilateral optic nerve damage; Terson’s syndrome; Cortical blindness
Consistent command following (A4)^†	No motor response (M0)^†	Quadriplegia
No visual response (V0) ^†	Functional communication (C2) ^†	Bilateral optic nerve damage; Terson’s syndrome; Cortical blindness
Visual fixation (V2) ^†	Functional communication (C2) ^†	3^rd and 4^th cranial nerve palsy; Ocular apraxia; Visual agnosia
Visual pursuit (V3)^†	Functional communication (C2)^†	Ocular apraxia; Visual agnosia
Object localization (V4)^†	Functional communication (C2)^†	Visual agnosia, hemineglect
Object recognition (V5)^†	No motor response (M0)^†	Quadriplegia
No motor response (M0)^†	Functional communication (C2)^†	Quadriplegia
Abnormal posturing (M1)^†	Functional communication (C2)^†	Severe spasticity
Flexion withdrawal (M2)^†	Functional communication (C2)^†	Severe spasticity, hypertonus or hypotonus
Localization to pain (M3) ^†	Functional communication (C2) ^†	Apraxia
Object manipulation (M4)^†	Functional communication (C2)^†	Severe spasticity, hypertonus or hypotonus; Apraxia
Automatic motor response (M5)^†	Functional communication (C2)^†	Object agnosia; Apraxia
No verbal response (Ve0)^†	Functional communication (C2)^†	Facial nerve palsy/Oromotor weakness
Oral reflexive movement (Ve1)^†	Functional communication (C2)^†
Vocalization (Ve2)^†	Functional communication (C2)^†
Functional communication (C2)^†	Eyes open with stimulation (Ar1)^†	N/A^*
Functional communication (C2)^†	Eyes open without stimulation (Ar2)^†	N/A^*

⁺

Non-observed subscore combinations

^†

p <.001

These combinations are clinically expected and likely to be improbable due to the population included in the sample (mainly VS/MCS patients).

^‡

Awake with preserved vision but unable to open the eyelids