Table 1.
Neurological and Speech and Language test scores for DY
| July 2010 | April 2013 | June 2014 | July 2015 | |
|---|---|---|---|---|
| Age, years | 53 | 56 | 57 | 58 |
| Disease duration, years | 5 | 8 | 9 | 10 |
| Years before death | 5.8 | 3.0 | 1.8 | 0.8 |
| Neurological/neuropsychological tests | ||||
| Mini Mental State Examination (/30) | 27 | 28 | 21 | 16 |
| Montreal Cognitive Assessment Battery (/30) | 25 | 27 | 18 | 7 |
| Clinical Dementia Rating Scale sum of boxes (/18) | 0 | 0 | 3.0 | 15 |
| Neuropsychiatric Inventory - Q (/36) | 9 | 4 | 5 | 8 |
| Frontal Assessment Battery (/18) | 16 | 13 | 11 | 0 |
| Western Aphasia Battery (WAB)-apraxia (/60) | 59 | 55 | 41 | 30 |
| Unified Parkinson’s Disease Rating Scale III (/132) | 5 | 18 | 38 | 72 |
| PSP Saccadic Impairment Scale (/5) | 0 | 1 | 1 | 3 |
| Auditory Verbal Learning Test - recognition (/15) | 11 | 13 | 12 | Untestable |
| Trail Making Test A | 19 | 29 | 51 | Untestable |
| Trail Making Test B | 60 | 118 | 244 | Untestable |
| Visual Object and Space Perception Battery -Incomplete letters (/20) | 20 | 20 | 20 | Untestable |
| Visual Object and Space Perception Battery - cubes (/10) | 8 | 8 | 9 | Untestable |
| Speech and language tests | ||||
| Token Test (/22) | 22 | 19 | 18 | 12 |
| WAB scores | ||||
| Aphasia quotient (/100) | 96.6 | 80 | 74.6 | Untestable |
| Fluency (/10) | 9 | 4 | 5.0 | Untestable |
| Spon. Speech (/20) | 19 | 12 | 13.0 | Untestable |
| AV comp (/10) | 10 | 10 | 10.0 | 9.8 |
| Repetition (/10) | 9.3 | 8.6 | 5.8 | Untestable |
| Naming (/10) | 10 | 9.4 | 8.5 | Untestable |
| Reading comp (/40) | 40 | 26 | 34.0 | 20.0 |
| Read commands (/20) | 20 | 14 | Untestable | Untestable |
| Write output (/10) | 33 | 32 | 13.5 | Untestable |
| Read Irregular (/10) | 9 | 10 | Untestable | Untestable |
| Read non-words (/10) | 8 | 9 | Untestable | Untestable |
| Write Irregular (/10) | 4 | 2 | 2.0 | Untestable |
| Write non-words (/10) | 7 | 8 | 0.0 | Untestable |
| Agrammatism in writing | No | Yes | Yes | Untestable |
| Agrammatism in speech | No | Yes | Yes | Untestable |
| Boston Naming Test (/15) | 12 | 10 | 7 | Untestable |
| Motor Speech Disorders Scale (/10) | 6 | 3 | 3 | 1 |
| Apraxia of Speech Rating Scale (/64) | 20 | 38 | 39 | Untestable |
| Action fluency | 16 | 12 | Untestable | Untestable |
| Letter fluency | 11 | 11 | Untestable | Untestable |
| Dysarthria (0–4) | 0 | 1 | 1.5 | Untestable |
| Non-verbal oral apraxia (/32) | 24 | 5 | 0 | 4 |