Table 1.
Virus | Host | Disease characteristics |
---|---|---|
GBV-B | Tamarins, marmosets and squirrel monkeys | Hepatotropic; mostly acute infection leading to liver inflammation and fibrosis |
CHV | Dogs | Dual tropism to respiratory system and liver; however not associated with liver disease |
EqHV | Horses | Hepatotropic; causes both acute and chronic infection with hepatic inflammation |
BovHepV | Cattle | Hepatotropic; few cases of chronic infection reported |
BHV | Bats | Apathogenic; potential natural reservoir for hepaciviruses |
RHV | Rats; mice | Hepatotropic; acute infection and mild liver pathology in mice; persistence in rats |
GBV-B, GB virus B; CHV, canine hepacivirus; EqHV, equine hepacivirus; BovHepV, bovine hepacivirus; BHV, bat hepacivirus; RHV, rodent hepacivirus.