Table 2.
LV Structural Parameters
| Time Point | |||||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| BR−2 | BR7 | BR21 | BR31 | BR70 | BR+0 | BR+3 | |
| LVEDV, ml | |||||||
| CONT | 137.8 (122.8–152.8) | 122.2 * (107.2–137.2) | 112.6 * (97.2–128.1) | 111.8 * (96.8–126.8) | 114.5 * (99.5–129.5) | 114.6 * (98.9–130.3) | 128.8 (113.7–144.0) |
| Ex | 142.5 (133.2–151.8) | 136.1 (126.8–145.5) | 140.0 (130.7–149.3) | 141.7 (132.4–151.1) | 136.2 (126.9–145.5) | 130.2 (120.6–139.8) | 144.2 (134.9–153.6) |
| ExT | 143.3 (133.2–153.4) | 141.7 (131.6–151.8) | 139.6 (129.2–150.0) | 141.4 (131.3–151.5) | 140.9 (130.8–151.0) | 142.0 (131.7–152.4) | 142.7 (132.6–152.8) |
| LVESV, ml | |||||||
| CONT | 46.5 (40.4–52.6) | 40.5 * (34.4–46.6) | 38.0 * (31.6–44.4) | 38.0 * (31.8–44.1) | 39.2 * (33.1–45.3) | 38.8 * (32.3–45.4) | 44.3 (38.0–50.5) |
| Ex | 53.5 (48.7–58.4) | 46.4 * (41.6–51.3) | 46.9 * (42.1–51.7) | 48.1 (43.3–52.9) | 44.6 * (39.8–49.4) | 48.1 (43.1–53.1) | 51.3 (46.4–56.1) |
| ExT | 49.2 (44.6–53.8) | 50.8 (46.2–55.5) | 47.0 (42.2–51.8) | 50.9 (46.3–55.5) | 48.9 (44.2–53.5) | 51.9 (47.1–56.8) | 52.8 (48.2–57.4) |
| LVIDd, cm | |||||||
| CONT | 5.22 (4.92–5.51) | 5.09 (4.79–5.38) | 4.92 * (4.63–5.22) | 4.84 * (4.55–5.14) | 4.84 * (4.55–5.14) | 4.77 * (4.48–5.07) | 5.02 * (4.72–5.31) |
| Ex | 5.21 (5.05–5.37) | 5.16 (5.00–5.32) | 5.08 (4.91–5.24) | 5.15 (4.99–5.31) | 5.11 (4.95–5.27) | 5.14 (4.98–5.30) | 5.10 (4.94–5.26) |
| ExT | 5.10 (4.81–5.39) | 5.08 (4.79–5.37) | 5.06 (4.76–5.35) | 5.02 (4.72–5.31) | 5.17 (4.88–5.46) | 5.16 (4.87–5.45) | 5.31 (5.01–5.60) |
| LV PW, cm | |||||||
| CONT | 0.81 (0.73–0.90) | 0.77 * (0.68–0.85) | 0.75 * (0.67–0.84) | 0.72 * (0.64–0.81) | 0.73 * (0.64–0.81) | 0.72 * (0.64–0.81) | 0.72 * (0.64–0.80) |
| Ex | 0.79 (0.71–0.86) | 0.80 (0.73–0.87) | 0.79 (0.71–0.86) | 0.81 (0.74–0.88) | 0.80 (0.73–0.87) | 0.81 (0.74–0.88) | 0.81 (0.74–0.88) |
| ExT | 0.71 (0.62–0.80) | 0.71 (0.62–0.80) | 0.69 (0.60–0.78) | 0.70 (0.61–0.79) | 0.72 (0.63–0.81) | 0.72 (0.63–0.81) | 0.73 (0.64–0.82) |
| LV IVSW, cm | |||||||
| CONT | 0.75 (0.65–0.84) | 0.76 (0.66–0.85) | 0.75 (0.66–0.84) | 0.71 (0.62–0.80) | 0.70 * (0.60–0.79) | 0.68 * (0.59–0.77) | 0.67 * (0.58–0.76) |
| Ex | 0.73 (0.67–0.79) | 0.73 (0.67–0.79) | 0.74 (0.68–0.80) | 0.75 (0.69–0.81) | 0.75 (0.69–0.81) | 0.75 (0.69–0.81) | 0.76 (0.70–0.82) |
| ExT | 0.68 (0.59–0.76) | 0.68 (0.60–0.76) | 0.69 (0.60–0.77) | 0.68 (0.60–0.76) | 0.68 (0.59–0.76) | 0.70 (0.61–0.78) | 0.69 (0.61–0.78) |
| LV mass, g | |||||||
| CONT | 142 (129–154) | 126 * (114–138) | 122 * (109–134) | 119 * (107–131) | 123 * (111–135) | 117 * (104–130) | 133 * (120–145) |
| Ex | 144 (136–152) | 146 (138–154) | 140 (132–148) | 144 (136–151) | 145 (137–152) | 140 (132–148) | 148 (140–156) |
| ExT | 152 (144–161) | 151 (142–160) | 153 (144–162) | 155 (146–163) | 153 (144–162) | 146 (137–155) | 150 (141–159) |
| LVM/EDV | |||||||
| CONT | 1.03 (0.97–1.09) | 1.04 (0.98–1.09) | 1.08 (1.02–1.10) | 1.07 (1.01–1.10) | 1.08 (1.02–1.12) | 1.02 (0.97–1.09) | 1.04 (0.98–1.09) |
| Ex | 1.07 (1.00–1.14) | 1.07 (1.00–1.14) | 1.09 (1.02–1.15) | 1.09 (1.02–1.16) | 1.10 (1.02–1.16) | 1.04 (0.97–1.11) | 1.06 (0.98–1.13) |
| ExT | 1.03 (0.97–1.09) | 1.04 (0.98–1.11) | 1.02 (0.96–1.06) | 1.02 (0.96–1.08) | 1.07 (1.01–1.12) | 1.08 (1.02 –1.15) | 1.02 (0.98–1.09) |
| LV length, cm | |||||||
| CONT | 8.09 (7.78–8.41) | 8.01 (7.70–8.32) | 7.97 (7.66–8.29) | 7.92 (7.61–8.23) | 7.78 * (7.46–8.09) | 7.73 * (7.41–8.04) | 7.88 * (7.56–8.19) |
| Ex | 8.37 (8.11–8.63) | 8.27 (8.01–8.53) | 8.28 (8.02–8.54) | 8.30 (8.04–8.55) | 8.27 (8.02–8.53) | 8.35 (8.09–8.60) | 8.33 (8.08–8.59) |
| ExT | 8.21 (7.93–8.48) | 8.12 (7.84–8.39) | 8.17 (7.90–8.45) | 8.13 (7.85–8.40) | 8.13 (7.86–8.41) | 8.10 (7.83–8.38) | 8.20 (7.93–8.48) |
BR, bed rest day; LV, left ventricular; EDV, end diastolic volume; ESV, end systolic volume; IDd, internal diameter diastole; PW, posterior wall; IVSW, intraventricular septal wall. Values are mean and 95% CI.
*
p<0.007 vs. BR−2.