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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2018 Jan 6:S0360-3016(17)34527-3. doi: 10.1016/j.ijrobp.2017.12.290

Table 3.

Summary of dose–response and probit model fit parameters for considered endpoints

Endpoint Events (n)/patients (n) D50 (Gy) γ50*
Grade 17/288 40.8 (25.5-∞) 0.95 (0.58–1.44)
 ≥3 liver enzymes
Grade 99/278 48.0 (43.6–65.9) 0.83 (0.37–1.31)
 ≥2 GI
Grade 25/399 87.1 (69.1–194.4) 1.22 (0.78–1.68)
 ≥3 GI

Abbreviations: γ50 = normalized dose-response gradient; D50 = dose for 50% complication probability.

Data in parentheses are 95% confidence intervals.

*

γ50 = 1/[m√(2π)], where m is a slope factor.