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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Res Microbiol. 2018 Feb 16;169(7-8):351–356. doi: 10.1016/j.resmic.2018.02.002

Fig. 2.

Fig. 2

Substrate specificities of MexEF-OprN and MexHI-OpmD from P. aeruginosa. When overproduced, and in the context of the outer membrane permeability barrier, the two pumps have overlapping substrate specificities and provide the same levels of resistance to structurally diverse fluoroquinolones. Their actual substrate specificities are distinct, with MexHI-OpmD selective for phenazines [59]. EtBr, ethidium bromide; PMS, phenazine methosulfate; PCA, phenazine-1-carboxylic acid.