Table 2.

CBVv values reported in the literature.

Reference	Species	Brain Region	Technique	CBVv (ml/100 ml)
(Ito et al., 2001)	Human	Cortex	PET	2.0±0.2
(An and Lin, 2002a)	Human	Whole brain	MRI	2.68 – 2.97
(An and Lin, 2002b)	Human	Whole brain	MRI	2.46±0.28
(An and Lin, 2003)	Human	Gray matter	MRI	4.0 – 5.5
		White matter		2.9 – 3.9
(Ito et al., 2005)	Human	Cortex	PET	1.9±0.5
(Bulte et al., 2007a)	Huamn	Whole brain	MRI	3.77±1.05
		Gray matter		3.93±0.90
		White matter		2.52±0.78
(He and Yablonskiy, 2007)	Human	Gray matter	MRI	1.75±0.13
		White matter	MRI	0.58±0.09
(He et al., 2008)	Rat	Whole brain	MRI	3.3±0.5
(Sedlacik and Reichenbach, 2010)	Human	Gray matter	MRI	2.54±0.40
		White matter		1.21±0.35
(Blockley et al., 2013a)	Human	Gray matter	MRI	2.18±0.41
		White matter		1.30±0.24

CBVv measured by most MRI methods developed to date reflects the signals from vessels with partially deoxygenated blood, which may include contributions from capillaries, venules and veins.

The percentage of CBVv/CBVtot depends on the CBVtot value used, which was estimated to be approximately 70–80% in (Piechnik et al., 2008; Sharan et al., 1989; van Zijl et al., 1998).