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. 2018 Aug 16;9:3278. doi: 10.1038/s41467-018-05751-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Nanopore resistive-pulse analysis of heparin, OSCS, and their mixture. a Superimposed scatter plots of 16 ppm heparin, OSCS and OSCS-contaminated heparin added to 4 M potassium chloride at +200 mV and measured using a ~13 nm pore. The colors in the legend correspond to the listed sample, and are blended (using transparency) in the plot where events from different samples overlap. b Recognition flags of heparin, OSCS and their mixture from four independent trials accurately identify the presence of the OSCS aliquot in the mixture. The red squares denote recognition of a species from the distribution of the corresponding property (column)