Table 1.
Clinical and biological parameters of patients among the three groups.
| Variable | HC (n = 20) | NCF (n = 29) | MCD (n = 29) | F | t | χ2 | P |
|---|---|---|---|---|---|---|---|
| Male [n (%)] | 11 (55.00) | 15 (51.70) | 15 (51.70) | 0.11 | 0.97 | ||
| Age (years) | 45.00 ± 8.90 | 43.10 ± 7.80 | 48.00 ± 7.20 | 2.87 | 0.06 | ||
| Education (years) | 11.10 ± 3.06 | 11.24 ± 2.46 | 10.83 ± 2.25 | 0.19 | 0.82 | ||
| Type of kidney diseases | 9.88 | 0.27 | |||||
| Chronic glomerulonephritis | — | 17 | 15 | ||||
| Diabetic nephropathy | — | 1 | 5 | ||||
| Benign arteriolar nephrosclerosis | — | 0 | 1 | ||||
| Polycystic kidney | — | 1 | 1 | ||||
| IgA nephropathy; | — | 0 | 1 | ||||
| Medullary sponge kidney | — | 0 | 1 | ||||
| Chronic kidney disease of unknown etiology | — | 6 | 5 | ||||
| Nephrotic syndrome | — | 3 | 0 | ||||
| Systemic lupus erythematosus nephropathy | — | 1 | 0 | ||||
| HB (g/L) | 142.20 ± 20.20 | 107.90 ± 13.00 | 108.90 ± 12.80 | 37.23 | <0.001*** | ||
| HCT (L/L) | 0.43 ± 0.05 | 0.33 ± 0.04 | 0.33 ± 0.04 | 38.54 | <0.001*** | ||
| WBC (10 9/L ) | 6.14 ± 1.26 | 5.99 ± 1.80 | 5.79 ± 1.61 | 0.29 | 0.75 | ||
| RBC (10 12/L ) | 4.94 ± 0.45 | 3.69 ± 0.50 | 3.69 ± 0.52 | 47.15 | <0.001*** | ||
| BUN (mmol/L) | 4.40 ± 0.85 | 27.55 ± 5.71 | 24.33 ± 4.42 | 179.30 | <0.001*** | ||
| Cr (umol/L) | 71.55 ± 8.65 | 1052.00 ± 195.90 | 965.00 ± 172.50 | 258.40 | <0.001*** | ||
| ALB (g/L) | 46.04 ± 2.49 | 40.04 ± 1.99 | 41.46 ± 4.03 | 24.40 | <0.001*** | ||
| Dialysis duration (months) | — | 71.52 ± 38.13 | 78.07 ± 47.39 | 0.58 | 0.56 | ||
| Calcium (mmol/L) | — | 2.15 ± 0.24 | 2.25 ± 0.29 | 1.34 | 0.18 | ||
| Phosphate (mmol/L) | — | 2.25 ± 0.70 | 2.07 ± 0.69 | 0.96 | 0.33 | ||
| PTH (pg/mL) | — | 534.3 ± 478.2 | 420.5 ± 362.6 | 1.02 | 0.31 | ||
| Dry weight (kg) | — | 61.42 ± 11.25 | 58.00 ± 8.28 | 1.32 | 0.19 |
Data are shown as means ± standard error of means (n = 20–29), ***p < 0.001. ALB: albumin; BUN: blood urea nitrogen; Cr: creatinine; HB: haemoglobin; HC: healthy control group; HCT: haematocrit; MCD: mild cognitive decline group; NCF: normal cognitive function group; PLT: blood platelet; PTH: parathyroid hormone RBC: red blood cell; WBC: white blood cell.