Table 1.
Baseline characteristics of healthy subjects, chronic HCV patients and HCV-spontaneous clearance group.
| Healthy control (n = 191) | Chronic HCV infection (n = 288) | HCV-Spontaneous clearance (n = 98) | |
|---|---|---|---|
| Age, years | 56 [18–93] | 63 [20–88] | 58[20–76] |
| Gender, (%) | |||
| Male | 63 (32.98) | 104 (36.11) | 40 (40.82) |
| Female | 128 (60.02) | 184 (63.89) | 58 (59.18) |
| Alanine aminotransferase, (IU/L) | 30 [12–54] | 63 [12–361] | 28 [12–92] |
| Aspartate aminotransferase, (IU/L) | 25 [12–34] | 54 [16–280] | 29.50 [14–65] |
| Gamma-glutamyltransferase, (IU/L) | NA | 73 [40–500] | 20 [14–65] |
| Total cholesterol, (g/L) | 1.91 [1.09–2.99] | 1.50 [0.84–2.87] | 1.10 [0.41–6.95] |
| HDL cholesterol, (g/L) | 0.50 [0.24–4.36] | 0.51 [0.14–1.27] | 0.79 [0.47–1.53] |
| LDL cholesterol, (g/L) | 1.10 [0.4–1.97] | 0.82 [0.3–5.11] | 3.15 [1.34–5.43] |
| Triglycerides, (g/L) | 1.11 [0.31–4.31] | 0.98 [0.48–2.13] | 0.46 [0.35–0.69] |
| Viral load, Log10 (IU/mL) | NA | 6.03 [1.78–7.50] | — |
| Viral genotypes (%) | |||
| 1/2 | — | 64.5/35.5 | — |
| MBOAT7 rs641738 variant, (%) | |||
| CC | 54 (28.27) | 90 (31.25) | 25 (25.51) |
| CT | 107 (56.02) | 144 (50) | 51 (52.04) |
| TT | 30 (15.71) | 54 (18.75) | 22 (22.45) |
| C allele | 0.563 ± 0.024 | 0.562 ± 0.020 | 0.515 ± 0.035 |
| T allele | 0.437 ± 0.024 | 0.438 ± 0.020 | 0.485 ± 0.035 |
NA: data not available.