Table 4.

Expression of IGF1, IGF1R, IGF2, IGF2R, and IGFBP1-6 transcripts.

	Oocytes*				Granulosa cells*
	Primordial follicles		Primary follicles		Primordial follicles		Primary follicles
Gene names	FPKM means	p-value	FPKM means	p-value	FPKM means	p-value	FPKM means	p-value
IGF1	2,696	0,25	1,928	0,404	2,826	0,222	1,767	0,018
IGF1R	4,610	0,091	7,582	0,017	7,758	0,016	7,149	0,018
IGF2	6,031	0,049	8,340	0,025	4,654	0,101	1,631	0,379
IGF2R	1,987	0,231	1,572	0,198	4,683	0,203	3,157	0,184
IGFB1	0,935	0,423	0,307	0,301	0,489	0,353	0,608	0,423
IGFB2	1,236	0,147	2,168	0,094	3,217	0,030	2,445	0,221
IGFB3	0,834	0,423	3,323	0,012	3,356	0,067	0,784	0,423
IGFB4	1,026	0,122	0,896	0,191	1,523	0,225	1,547	0,103
IGFB5	5,071	0,052	6,283	0,007	7,116	0,005	5,733	0,052
IGFB6	–	–	–	–	1,439	0,303	0,056	0,423

Gene names are followed by the mean FPKM and p-values for human oocytes and granulosa cells from primordial and primary follicels, as indicated.

^*Data extracted from Ernst et al. (2018) and Kuijjer et al. (2013).