Table 3.
Two-way ANOVA Bonferroni comparisonsa
| Figure | Comparison | p | Figure | Comparison | p |
|---|---|---|---|---|---|
| 4C | Sham/veh versus Sham/met | <0.9999 | 5B, ipsilateral | L2/L3 ipsilateral Sham/veh versus SNI/veh, IL | 0.2666 |
| Sham/veh versus SNI/veh BL | 0.6866 | L5/L6 ipsilateral Sham/veh versus SNI/veh ipsilateral, IL | 0.0408 | ||
| Sham/veh versus SNI/met BL | 0.5082 | 5B, contralateral | L2/L3 contralateral Sham/veh versus SNI/veh, IL | 0.7179 | |
| Sham/met versus SNI/veh BL | >0.9999 | L5/L6 contralateral Sham/veh versus SNI/veh contralateral, IL | 0.5994 | ||
| Sham/met versus SNI/met BL | >0.9999 | 5C, ipsilateral | L2/L3 ipsilateral Sham/veh versus SNI/veh, IL females | >0.9999 | |
| SNI/veh versus SNI/met BL | >0.9999 | L5/L6 ipsilateral Sham/veh versus SNI/veh contralateral, IL Fem | >0.9999 | ||
| Sham/veh versus Sham/met 14 | >0.9999 | 5C, contralateral | L2/L3 contralateral Sham/veh versus SNI/veh, IL females | 0.9271 | |
| Sham/veh versus SNI/veh 14 | <0.0001 | L5/L6 contralateral Sham/veh versus SNI/veh contralateral, IL | >0.9999 | ||
| Sham/veh versus SNI/met 14 | <0.0001 | 5D, ipsilateral | L2/L3 ipsilateral Sham/veh versus SNI/veh, PrL | 0.4175 | |
| Sham/met versus SNI/veh 14 | <0.0001 | L5/L6 ipsilateral Sham/veh versus SNI/veh contralateral, PrL | >0.9999 | ||
| Sham/met versus SNI/met 14 | <0.0001 | 5D, contralateral | L2/L3 contralateral Sham/veh versus SNI/veh, PrL | >0.9999 | |
| SNI/veh versus SNI/met 14 | >0.9999 | L5/L6 contralateral Sham/veh versus SNI/veh contralateral, PrL | >0.9999 | ||
| Sham/veh versus Sham/met 15 | >0.9999 | 5E, ipsilateral | L2/L3 ipsilateral Sham/veh versus SNI/veh, Cg1 | >0.9999 | |
| Sham/veh versus SNI/veh 15 | <0.0001 | L5/L6 ipsilateral Sham/veh versus SNI/veh contralateral, Cg1 | 0.9006 | ||
| Sham/veh versus SNI/met 15 | <0.0001 | 5E, contralateral | L2/L3 contralateral Sham/veh versus SNI/veh, Cg1 | 0.8647 | |
| Sham/met versus SNI/veh 15 | <0.0001 | L5/L6 contralateral Sham/veh versus SNI/veh contralateral, Cg1 | 0.3809 | ||
| Sham/met versus SNI/met 15 | <0.0001 | 6B | L2/L3 ipsilateral Sham/veh versus SNI/veh, IL | 0.9231 | |
| SNI/veh versus SNI/met 15 | 0.9150 | L5/L6 ipsilateral Sham/veh versus SNI/veh ipsilateral, IL | 0.0067 | ||
| Sham/veh versus Sham/met 16 | >0.9999 | L2/L3 contralateral Sham/veh versus SNI/veh, IL | >0.9999 | ||
| Sham/veh versus SNI/veh 16 | <0.0001 | L5/L6 contralateral Sham/veh versus SNI/veh contralateral, IL | 0.0230 | ||
| Sham/veh versus SNI/met 16 | 0.0436 | 6C | L2/L3 ipsilateral Sham/veh versus SNI/veh, IL | 0.0908 | |
| Sham/met versus SNI/veh 16 | <0.0001 | L5/L6 ipsilateral Sham/veh versus SNI/veh contralateral, IL | 0.7201 | ||
| Sham/met versus SNI/met 16 | 0.0090 | L2/L3 contralateral Sham/veh versus SNI/veh, IL | 0.2153 | ||
| SNI/veh versus SNI/met 16 | 0.0043 | L5/L6 contralateral Sham/veh versus SNI/veh contralateral, IL | 0.1695 | ||
| Sham/veh versus Sham/met 17 | >0.9999 | 6D | Sham/veh versus SNI/veh ipsilateral L2/L3, PrL | >0.9999 | |
| Sham/veh versus SNI/veh 17 | <0.0001 | Sham/veh versus SNI/veh ipsilateral L5/L6, PrL | >0.9999 | ||
| Sham/veh versus SNI/met 17 | >0.9999 | Sham/veh versus SNI/veh contralateral L2/L3, PrL | >0.9999 | ||
| Sham/met versus SNI/veh 17 | <0.0001 | Sham/veh versus SNI/veh contralateral L5/L6, PrL | >0.9999 | ||
| Sham/met versus SNI/met 17 | >0.9999 | 6E | Sham/veh versus SNI/veh ipsilateral L2/L3, Cg1 | >0.9999 | |
| SNI/veh versus SNI/met 17 | <0.0001 | Sham/veh versus SNI/veh ipsilateral L5/L6, Cg1 | >0.9999 | ||
| Sham/veh versus Sham/met 18 | >0.9999 | Sham/veh versus SNI/veh contralateral L2/L3, Cg1 | >0.9999 | ||
| Sham/veh versus SNI/veh 18 | <0.0001 | Sham/veh versus SNI/veh contralateral L5/L6, Cg1 | >0.9999 | ||
| Sham/veh versus SNI/met 18 | 0.6051 | 6F | L5/L6 ipsilateral: SNI/veh versus Sham/veh, IL | 0.0041 | |
| Sham/met versus SNI/veh 18 | <0.0001 | L5/L6 ipsilateral: SNI/veh versus Sham/gp, IL | 0.0134 | ||
| Sham/met versus SNI/met 18 | 0.4778 | L5/L6 ipsilateral: SNI/veh versus SNI/gp, IL | >0.9999 | ||
| SNI/veh versus SNI/met 18 | <0.0001 | L5/L6 contralateral: SNI/veh versus Sham/veh, IL | 0.0143 | ||
| Sham/veh versus Sham/met 19 | 0.3421 | L5/L6 contralateral: SNI/veh versus Sham/gp, IL | >0.9999 | ||
| Sham/veh versus SNI/veh 19 | <0.0001 | L5/L6 contralateral: SNI/veh versus SNI/gp, IL | >0.9999 | ||
| Sham/veh versus SNI/met 19 | >0.9999 | 6G | L5/L6 ipsilateral: SNI/veh 1d versus Sham/veh, IL | 0.0014 | |
| Sham/met versus SNI/veh 19 | <0.0001 | L5/L6 ipsilateral: SNI/veh 1d versus Sham/met 1d, IL | 0.0058 | ||
| Sham/met versus SNI/met 19 | 0.4576 | L5/L6 ipsilateral: SNI/veh 1d versus SNI/met 1d, IL | 0.0064 | ||
| SNI/veh versus SNI/met 19 | <0.0001 | L5/L6 ipsilateral: SNI/veh 1d versus SNI/veh 14d, IL | >0.9999 | ||
| Sham/veh versus Sham/met 21 | >0.9999 | L5/L6 ipsilateral: SNI/veh 1d versus SNI/met 14d, IL | 0.0036 | ||
| Sham/veh versus SNI/veh 21 | <0.0001 | L5/L6 contralateral: SNI/veh 1d versus Sham/veh, IL | 0.0072 | ||
| Sham/veh versus SNI/met 21 | >0.9999 | L5/L6 contralateral: SNI/veh 1d versus Sham/met 1d, IL | 0.0291 | ||
| Sham/met versus SNI/veh 21 | <0.0001 | L5/L6 contralateral: SNI/veh 1d versus SNI/met 1d, IL | 0.9947 | ||
| Sham/met versus SNI/met 21 | >0.9999 | L5/L6 contralateral: SNI/veh 1d versus SNI/veh 14d, IL | >0.9999 | ||
| SNI/veh versus SNI/met 21 | <0.0001 | L5/L6 contralateral: SNI/veh 1d versus SNI/met 14d, IL | 0.0218 | ||
| 3-1A | BL: SNI/veh versus SNI/GP (100 mg/kg) | 0.7862 | |||
| SNI/gp 100 mg/kg comparison shown | NC 2 week: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | |||
| 30 min: SNI/veh versus SNI/GP (100 mg/kg) | 0.0083 | ||||
| 1 h: SNI/veh versus SNI/GP (100 mg/kg) | <0.0001 | ||||
| 2 h: SNI/veh versus SNI/GP (100 mg/kg) | <0.0001 | ||||
| 3 h: SNI/veh versus SNI/GP (100 mg/kg) | <0.0001 | ||||
| 4 h: SNI/veh versus SNI/GP (100 mg/kg) | <0.0001 | ||||
| 5 h: SNI/veh versus SNI/GP (100 mg/kg) | <0.0001 | ||||
| 6 h: SNI/veh versus SNI/GP (100 mg/kg) | <0.0001 | ||||
| 6.5 h: SNI/veh versus SNI/GP (100 mg/kg) | 0.0645 | ||||
| 7 h: SNI/veh versus SNI/GP (100 mg/kg) | 0.0919 | ||||
| 7.5 h: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | ||||
| 3-1B | BL: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | |||
| SNI/gp 100 mg/kg comparison shown | NC 2 week: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | |||
| 30 min: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | ||||
| 1 h: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | ||||
| 2 h: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | ||||
| 3 h: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | ||||
| 4 h: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | ||||
| 5 h: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | ||||
| 6 h: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | ||||
| 6.5 h: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | ||||
| 7 h: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 | ||||
| 7.5 h: SNI/veh versus SNI/GP (100 mg/kg) | >0.9999 |
aveh, Vehicle; GP, gabapentin; met, metformin; NC = neuropathic check.