Table 5.
Summary of the clusters in relation to the literature
| Cluster A | Cluster B | Cluster C | Cluster D | Cluster E | Cluster F | Cluster G | |
|---|---|---|---|---|---|---|---|
| Proposed types (current study) | Microglomerular | ET | Uniglomerular | Oligoglomerular | Vertical superficial tufted | Polyglomerular | Horizontal superficial tufted |
| Corresponding previous nomenclature | Periglomerular | ET (Pinching and Powell, 1971) | Periglomerular (Pinching and Powell, 1971) | Periglomerular | Superficial tufted or ET with basal dendrite (Antal et al., 2006) | Superficial short axon (Pinching and Powell, 1971; Aungst et al., 2003) | Superficial tufted or ET with basal dendrite (Wachowiak and Shipley, 2006; Antal et al., 2006) |
| Uniglomerular (Kiyokage et al., 2010) | Oligoglomerular (Kiyokage et al., 2010) | Polyglomerular (Kiyokage et al., 2010) | |||||
| Extension | Tuft within parts of 1 glomerulus | Extensive tuft within 1 glomerulus | 1–3 glomeruli | 2–6 glomeruli | Tuft within 1 glomerulus, basal dendrites extending in EPL below the soma | ≥7 glomeruli | Tuft within 1 glomerulus, lateral dendrite extending parallel to the GL |
| Median soma area (μm2) | 42.2 | 90.0 | 55.9 | 87.5 | 98.9 | 79.0 | 107.9 |
| Median some diameter (μm) | 6.4 | 9.4 | 7.4 | 9.3 | 9.8 | 8.8 | 10.3 |
| Input (current study) | hSTC | ETC | ETC, hSTC | ETC | |||
| Input (from the literature) | Unknown | OSN, ETC | ETC, TC, MC | ETC, OSN | Unknown | ETC, OSN | Unknown |
| Function | Unclear | Feedforward excitation (Hayar et al., 2004a, 2005; De Saint Jan et al., 2009; Gire et al., 2012; Tatti 2014) | Feedback and feedforward inhibition (Murphy et al., 2005; Shao et al., 2009; Gire et al., 2012; Najac et al., 2015) | Lateral inhibition between local glomeruli (Kiyokage et al., 2010; Whitesell et al., 2013) | Unknown | Lateral inhibition between distant glomeruli (Aungst et al., 2003; Whitesell et al., 2013) | Feedforward excitation (current study) |
| Expected molecular subtypes | CR, GAD65 (Kosaka et al., 2007; Parrish-Aungst et al., 2007; Whitman and Greer, 2007; Kiyokage et al., 2010) | VGLUT2, VGLUT3 (Tatti et al., 2014) | CB, GAD65 (Kosaka et al., 2007; Parrish-Aungst et al., 2007; Whitman and Greer, 2007) | TH, GAD67 (Kosaka et al., 2007; Parrish-Aungst et al., 2007; Whitman and Greer, 2007; Kiyokage et al., 2010) | Unknown | TH, GAD67 (Kosaka et al., 2007; Parrish-Aungst et al., 2007; Whitman and Greer, 2007; Kiyokage et al., 2010) | Vasopressin (Tobin et al., 2010) |