Figure 2.

Relationship between age and univariate and multivariate effects within ROIs. a, Univariate subsequent memory effects (mean activity for remembered − forgotten), showing increased activity with age in PFC but not PVC. b, Spread of multivariate responses predicting subsequent memory (SD of fitted MVB voxel weights), showing reduced spread of responses with age in both ROIs. c, Univariate effects of load (positive linear contrast) during STM maintenance, showing increased activity with age in both ROIs. e, Spread of multivariate responses during STM maintenance predicting increasing load, showing reduced spread of responses with age in both ROIs. Red and blue lines are robust-fitted second-order polynomial regression lines and shaded areas show 95% confidence intervals. e, PVC (blue) and PFC (red) ROIs overlaid on sagittal section (x = +36) of a canonical T1-weighted brain image. Note that y-axis scales are not comparable across tasks.