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. 2018 Jun 28;16(3):2935–2948. doi: 10.3892/ol.2018.9044

Table IV.

HR of interleukin-6R mRNA for OS.

Univariate analysis Multivariate analysis
Datasets HR LCI UCI P-valuea HR LCI UCI P-valueb
LUAD
  GSE14814c 0.201 0.092 0.443 <0.001 0.190 0.076 0.474 <0.001
  GSE30219d 0.237 0.093 0.603 0.003 0.215 0.081 0.566 0.002
  GSE37745c 0.659 0.416 1.044 0.076 0.589 0.303 1.147 0.120
  GSE42127c 0.559 0.267 1.168 0.122 0.693 0.319 1.505 0.354
  GSE50081e 0.493 0.287 0.846 0.010 0.656 0.370 1.163 0.149
  GSE68465f 0.492 0.375 0.646 <0.001 0.566 0.426 0.752 <0.0001
  GSE68571g 0.492 0.217 1.117 0.089 0.602 0.256 1.418 0.246
  TCGAh 0.617 0.436 0.873 0.006 0.515 0.344 0.772 0.001
LUSC
  GSE14814i 1.701 0.669 4.323 0.264 1.589 0.597 4.227 0.354
  GSE30219d 1.440 0.748 2.775 0.275 1.559 0.797 3.050 0.194
  GSE37745c 2.599 1.344 5.029 0.005 4.071 1.436 11.537 0.008
  GSE42127c 9.906 1.321 74.297 0.026 8.577 1.084 67.868 0.042
  GSE50081j 0.442 0.149 1.312 0.141 0.387 0.119 1.257 0.114
  TCGAh 1.375 0.954 1.981 0.088 1.308 0.899 1.903 0.161

P<0.05 indicated in bold.

a

Data were compared using Univaruate Cox's proportional hazards model

b

data were compared using multivariate Cox's proportional hazards model. Multivariate analysis adjusted variables

c

age, sex, stage, post-treatment

d

age, sex, T, N

e

age, sex, stage, T, N

f

age, sex, T, N, adjuvant-chemotherapy, adjuvant-radio-therapy

g

age, sex, tumor size, stage

h

age, sex, stage, T, N, M

i

age, stage, post-treatment

j

age, sex, stage, T. HR, hazard ratio; LCI, lower 95% confidence interval; UCI, upper 95% confidence interval; TCGA, The Cancer Genome Atlas; LUAD, adenocarcinoma; LUSC, squamous cell carcinoma.