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. 2018 Jun 19;16(3):3045–3053. doi: 10.3892/ol.2018.8993

Figure 1.

Figure 1.

Immunohistochemical analyses of intratumoral and peritumoral lymphocytes. Immunohistochemical staining of tumor-infiltrating (A) Foxp3+ T cells and (B) CD8+ T lymphocytes in invasive breast cancer. A diffuse pattern of intratumoral lymphocytes was observed. By contrast, peritumoral lymphocytes formed a lymphoid aggregate (×10 objective lens). There were markedly more Foxp3+ Tregs in the (C) peritumoral area than the (E) intratumoral areas. There was an increased number of CD8+ lymphocytes in the (D) peritumoral area than the (F) intratumoral areas. A and B, ×10 objective lens; B-E, ×40 objective lens. CD, cluster of differentiation; Foxp3, forkhead box 3.