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. 2018 Jun 20;16(3):3038–3044. doi: 10.3892/ol.2018.8999

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Copyright: © Jiang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — ADAM9 knockdown inhibits the proliferation, migration and invasion of 786-O and A498 cells. (A) ADAM9 siRNA decreased ADAM9 mRNA expression in 786-O and A498 cells as determined using reverse transcription-quantitative polymerase chain reaction. (B) ADAM9 siRNA inhibited the expression of ADAM9 protein in 786-O and A498 cells as determined using western blotting. (C) Cell counting kit-8 assay showed that ADAM9 siRNA suppressed the proliferation of 786-O and A498 cells. (D) ADAM9 siRNA repressed the migratory and invasive abilities of 786-O and A498 cells. *P<0.05 compared with the respective control. ADAM9, ADAM metallopeptidase domain 9; NC, negative control; siRNA, small-interfering RNA.