Knockdown of lncRNA-ECM reduces the invasion and migration of ESCC cells. (A and B) The cell invasion ability decreased following knock-down of lncRNA-ECM. (C and D) The cell migration ability decreased following knock-down lncRNA-ECM. **P<0.01. Magnification, ×200. Lnc, long-non coding; ECM, extracellular matrix; NC, negative control; ESCC, esophageal squamous cell carcinoma.