Table II.
Correlation analyses of KIAA1456 expression in lung cancer tissue with clinicopathological parameters.
| KIAA1456 staining | |||||
|---|---|---|---|---|---|
| Clinicopathological parameters | n | Low expression (n, %) | High expression (n, %) | P-valuea | χ2 |
| Sex | 0.118 | 3.271 | |||
| Male | 56 | 29 (51.8) | 27 (48.2) | ||
| Female | 34 | 16 (47.1) | 18 (52.9) | ||
| Age (years) | 0.154 | 2.147 | |||
| ≤60 | 53 | 23 (43.4) | 30 (56.6) | ||
| >60 | 37 | 21 (56.8) | 16 (43.2) | ||
| Max. tumor diameter | 0.125 | 4.158 | |||
| ≤3 cm | 42 | 19 (45.2) | 23 (54.8) | ||
| >3 cm | 48 | 27 (56.2) | 21 (43.8) | ||
| Histology | 0.424 | 3.297 | |||
| Adenocarcinoma | 68 | 32 (47.1) | 36 (52.9) | ||
| Squamous cell carcinoma | 16 | 8 (50) | 8 (50) | ||
| Others | 6 | 4 (66.7) | 2 (33.3) | ||
| pT stage | <0.01 | 6.713 | |||
| pT1 | 27 | 7 (25.9) | 20 (74.1) | ||
| pT2 | 40 | 19 (47.5) | 21 (52.5) | ||
| pT3-pT4 | 23 | 18 (78.3) | 5 (21.7) | ||
| pN stage | <0.01 | 7.291 | |||
| pN0 | 45 | 17 (37.8) | 28 (62.2) | ||
| pN1 | 17 | 7 (41.2) | 10 (58.8) | ||
| pN2-pN3 | 28 | 20 (71.4) | 8 (28.6) | ||
| TNM stage | <0.01 | 6.246 | |||
| I | 33 | 8 (24.2) | 25 (75.8) | ||
| II–III | 57 | 32 (56.1) | 25 (43.9) | ||
| Pathological stage | <0.01 | 6.349 | |||
| G1-G2 | 61 | 23 (37.7) | 38 (62.3) | ||
| G3 | 29 | 21 (72.4) | 8 (27.6) | ||
a
Chi-square test, p<0.05 suggests that the difference is statistically significant. KIAA1456, tRNA methyltransferase 9-like protein.